2005/2006

Statistical Analysis of Complex Event History Data

Natural Sciences

Principal investigators

Odd Olai
Aalen

Professor
University of Oslo (UiO)
Year at CAS

Ørnulf
Borgan

Professor
University of Oslo (UiO)
Year at CAS

Abstract

Survival and Event history analysis denote a set of statistical methods used to analyse and describe life times, durations and more complex event histories. It is the traditional tool for analysing incidence and prognosis of cancer and other chronic diseases, but is also of importance in fields like demography, social science, economics, and technical reliability. Although a large body of theory and methods exists, the methodology for analysing complex event histories, with many events and concomitant information (covariates) measured at the entry to the study and during the follow up, is still not well developed. One example would be a clinical study where success of a treatment cannot only be measured by survival, but also by how the course of the disease develops, e.g., with respect to periods of remission and quality of life. The purpose of the project at the Norwegian Centre for Advanced studies is to contribute to the development of statistical methodology for complex event history data. In particular we aim to
- study connections with modern methods of causality
- study methods that account in a realistic way for unobserved heterogeneity
- study methods for proper inclusion of high dimensional gene expression data in the analysis of survival and event history data
- develop alternatives to the commonly used Cox regression that are better suited to handle dynamic covariates and time-varying covariate effects
- develop useful summary measures of complex event histories

Fellows

Per Kragh
Andersen

Professor
University of Copenhagen
Year at CAS
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Christine
Böhm

University of Freiburg
Year at CAS

Hege Marie
Bøvelstad

Ph. D. Candidate
University of Oslo (UiO)
Year at CAS
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Vanessa
Didelez

Dr.
University College London
Year at CAS

Geir Egil
Eide

Associate Professor
Haukeland University Hospital
Year at CAS
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Daniel Mark
Farewell

Research Fellow
Cardiff University
Year at CAS
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Vernon Todd
Farewell

Senior Researcher
Medical Research Council Biostatistics Unit
Year at CAS
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Johan
Fosen

Senior Advisor
Statistics Norway
Year at CAS
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Arnoldo
Frigessi

Professor
University of Oslo (UiO)
Year at CAS

Axel
Gandy

Lecturer
Imperial College London
Year at CAS

Håkon K.
Gjessing

Professor
Norwegian Institute of Public Health
Year at CAS

Jon Michael
Gran

Research Fellow
University of Oslo (UiO)
Year at CAS

Nina
Gunnes

Research Fellow
University of Oslo (UiO)
Year at CAS

Robin
Henderson

Professor
Newcastle University
Year at CAS

Nils Lid
Hjort

Professor
University of Oslo (UiO)
Year at CAS

Niels
Keiding

Professor
University of Copenhagen
Year at CAS

Jan Terje
Kvaløy

Associate Professor
University of Stavanger (UiS)
Year at CAS

Bo Henry
Lindqvist

Professor
Norwegian University of Science and Technology (NTNU)
Year at CAS
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Torben
Martinussen

Associate Professor
The Royal Veterinary and Agricultural University
Year at CAS

Ståle
Nygård

Research Fellow
University of Oslo (UiO)
Year at CAS

Sven Ove
Samuelsen

Associate Professor
University of Oslo (UiO)
Year at CAS

Thomas Harder
Scheike

Lecturer
University of Copenhagen
Year at CAS

Hans C.
van Houwelingen

Professor
Leiden University Medical Center
Year at CAS